STUDY OF A NEW COMBINATION OF PHOTOSENSITIZER AND LASER RADIATION FOR ANTIMICROBIAL PHOTODYNAMIC HERAPY
Keywords:
photosensitizer, laser radiation, antimicrobial photodynamic therapy, microflora of dental plaqueAbstract
The lack of effectiveness of traditional tools and methods of antimicrobial therapy in the treatment of dental diseases, the presence of side effects and the development of microbial resistance to antiseptics and antibiotics has created a need to find new ways of antimicrobial exposure. This method has become the antimicrobial photodynamic therapy The purpose of this research was to study the antimicrobial action combined impact ethacridine lactate solution and laser radiation with a wavelength of 445 nm on the microflora of dental plaque. The experiment was conducted 40 sowings. The effectiveness of the method was evaluated by the decrease of colony forming units. Comparing the output level of the colonies that grew (control sowing) and the number of colonies that grew after photodynamic therapy, we have found the decrease in the total number of microbial: 8 ± 0,92 × 103 – in control and 3,76 ± 0,28 × 102 – in research. Thus, the experiment was found that the combined use of ethacridine lactate solution and blue laser radiation has antimicrobial effect, as evidenced by a decrease in the number of CFU/ml of the microflora of dental plaque.
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