CLINICAL AND IMM UNOLOGICAL FEATURES OF THE COURSE OF ACUTE INFLAMM ATORY COMPLICATIONS OF DENTAL IMPLANTATION
DOI:
https://doi.org/10.35220/2523-420X/2024.2.5Keywords:
dental implantation, inflammatory complications, immunity, immunoglobulinsAbstract
The methods of predicting various types of inflammatory complications of dental implantation, their causes and factors contributing to their development have not been sufficiently studied. At the same time, it is known that the course of the inflammatory process, its tendency to a protracted chronic course, as well as an acute manifestation, is largely determined by the state of local immunoreactivity. Purpose of the study. The aim of the study was to establish the clinical-diagnostic and prognostic value of immune proteins (IgG, SIgA, IgM) in patients with various inflammatory complications that occur immediately after surgical installation of dental intraosseous implants. Materials and methods. 92 persons aged 42 to 64 years who needed dental implantation were under observation. The number of intraosseous dental implants installed on the lower and upper jaws did not differ much and was 92 (45.7%) and 109 (54.2%), respectively. The control group included 24 practically healthy blood donors, similar in gender and age, with intact teeth and periodontal tissues. The objective condition of the oral cavity and gums at the time of admission to the clinic and in subsequent study periods was studied using WHO-recommended indices and samples. Research results. As a result of the conducted research, differences in most indicators of local humoral protection in various clinical forms of inflammatory complications that occurred in the early period after the installation of dental intraosseous implants were revealed. With a weak immunological response, the inflammatory process in the peri-implant zone acquires a mild, sluggish course with a tendency to protracted manifestation – chronicity. Acute, systemic inflammation in peri-implant tissues is combined with activation of synthesis of IgG, IgM and SIgA. The development of a pronounced clinical picture of chronic inflammatory complications is possible against the background of high IgG content and some decrease in SIgA and IgM levels.
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