THE ROLE OF MATRIX METALLOPROTEINASE-8 IN THE DIAGNOSIS OF INFLAMMATORY PERIODONTAL DISEASES IN ORTHODONTIC TREATMENT WITH FIXED EQUIPMENT
DOI:
https://doi.org/10.35220/2523-420X/2019.1.9Keywords:
matrix metalloproteinase-8, chronic catarrhal gingivitis, orthodontic treatment, oral fluidAbstract
One of the main etiological risk factors and pathogenetic mechanisms for the development of inflammatory perio-dontal diseases is malocclusion or dental abnormalities. It is known that a high percentage of complications, namely, the development of inflammatory diseases in periodontal tissues are detected during or after orthodontic treatment.
The purpose of this study. Study of matrix metalloproteinase-8 in patients with chronic catarrhal gingivitis in the dynamics of orthodontic treatment with fixed equipment.
Materials and methods of research. We conducted studies of 34 young people aged 16 to 25 years, including 21 girls (61.8 %) and 13 boys (38.2%), who underwent orthodontic treatment using fixed structures. All patients were di-agnosed with chronic catarrhal gingivitis that occurred during orthodontic treatment.
The results of the study and their discussion. The following values of matrix metalloproteinase – 8 (1.85 ± 0.09 ng/ml) were found in the oral fluid of patients with dental anomalies and fixed structures of orthodontic devices in the oral cavity at the beginning of orthodontic treatment, which significantly differed from the values in healthy people without periodontal tissue pathology (0.27 ± 0.01 ng/ml), and this can be associated, in our opinion, with inflammation in periodontal tissues, which occurs against the background of dental anomalies and other orthodontic pathology.
Our research has shown that when using fixed orthodontic devices, periodontal tissue injury occurs and this can lead to the occurrence of chronic catarrhal gingivitis. In addition, an important role in the occurrence of inflammatory processes in periodontal tissues also belongs to various dental anomalies in the oral cavity.
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