ANALYSIS OF BIOCHEMICAL PARAMETERS IN ORAL FLUID OF CHILDREN FROM THE DANUBE REGION DURING COMPLEX DENTAL TREATMENT
DOI:
https://doi.org/10.35220/2523-420X/2023.1.10Keywords:
children of the Danube region, prevention of dental diseases, biochemical parameters of oral liquidAbstract
Purpose of the study To assess the impact of complex dental treatment on the biochemical parameters of oral fluid in children from the Danube Region. Materials and methods. The study was conducted on 97 children from the Danube region aged 6 years (28 people in the main group and 22 people in the comparison group) and 12 years (26 people in the main group and 21 people in the comparison group). Children from the comparison group received oral sanitation and occupational hygiene, while children from the main group received an additional complex of adaptogens, anti-inflammatory, antioxidant, membrane-stabilizing and remineralizing drugs. The results obtained indicate that the developed therapeutic and preventive complex, which included anti-inflammatory, antioxidant, membrane-stabilizing, remineralizing drugs and adaptogens, had a fairly positive effect on the state of oral health in children of the Danube Region during complex dental treatment. In particular, an increase in the content of mineral components, such as calcium and phosphorus, in the oral fluid of children after performing activities in the main group compared to the comparison group was found. Positive changes in the biochemical parameters of oral fluid were also found, in particular, an increase in lysozyme and catalase activity, and a decrease in urease activity and Malone dialaldehyde content. These changes indicate an improvement in nonspecific antimicrobial, antioxidant protection, the degree of contamination and the level of lipid peroxidation in the oral cavity of children. Conclusion. So, we can conclude that the developed therapeutic and preventive complex is effective and can be recommended for use in the prevention and treatment of oral diseases in children of the Danube Region.
References
Mokijenko A. V., & Koval'chuk L. J. (2014). Obg'runtuvannja doslidzhen' vplyvu vodnogo faktora na zdorov’ja naselennja (ogljad literatury) [Substantiation of studies on the influence of the water factor on public health (literature review)]. Gigijena naselenyh misc' – Hygiene of populated areas, 64, 67-76 [in Ukrainian].
Koval'chuk L.J., & Mokijenko A.V. (2015). Gigijenichna ocinka stanu vodnyh ob’jektiv u miscjah vodokorystuvannja naselennja ukrai'ns'kogo Prydunav’ja [Hygienic assessment of the state of water bodies in places of water use of the population of the Ukrainian Danube Region]. Medychni perspektyvy – Medical perspectives, 20, 1, С. 132-139 [in Ukrainian].
Velikov, M. I., & Djen'ga, O. V. (2023). Efektyvnist' stomatologichnoi' profilaktyky u ditej, jaki prozhyvajut' v
Prydunav’i'. [Effectiveness of dental prevention in children living in the Danube Region]. Visnyk stomatologii' – Bulletin of Dentistry, 47, 1(122), 15–20 [in Ukrainian].
Koval'chuk, L.J., & Nadvorny,j N.N. (2013). Strategija i taktyka sanitarno-gigijenichnyh ta medykoekologichnyh doslidzhen' Ukrai'ns'kogo Prydunav’ja. [Strategy and tactics of sanitary-hygienic and medical-Environmental Research of the Ukrainian Danube Region]. Aktual'ni problemy transportnoi' medycyny – Actual problems of transport medicine, 4 (34), 32-36 [in Ukrainian].
Gorohivs'kyj, V. V., & Djen'ga, O. V. (2022). Stomatologichnyj status ditej z karijesom zubiv pid dijeju rozroblenyh profilaktychnyh zahodiv vkljuchajuchyh minerol [Dental status of children with dental caries under the influence of developed preventive measures including mineral]. Innovacii' v stomatologii' – Innovations in dentistry, 1, 39–42 [in Ukrainian].
Djen'ga, O. V., Dorosh, I. V., Rozhko, P. D., & Hodorchuk, K. V. (2021). Stomatologichnyj status ditej z juvenil'nym revmatoi'dnym artrytom v procesi kompleksnogo likuvannja [Dental status of children with juvenile rheumatoid arthritis in the process of complex treatment]. Colloquium-journal, 24(111), 43–46 [in Ukrainian].
Edited by Seyed Mohammad Reza Parizadeh, Majid Ghayour Mobarhan. (2011). 12th Iranian Congress of Biochemistry & 4th International Congress of Biochemistry and Molecular Biology, Mashhad, Iran, September 6-9 2011.V. 44, Issue 13, Supplement, P. S1-S366.
Mario Taba Jr Janet Kinney, Amy S Kim, & William V Giannobile. (2005). Diagnostic biomarkers for oral and periodontal diseases. Dent Clin North Am.,49(3), 551-71 doi: 10.1016/j.cden.2005.03.009.